Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923849 | 0.94 | CYP1A2 (0.48) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL8925411 | 0.89 | CYP1A2 (0.57) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL8922848 | 0.88 | CYP1A2 (0.47) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL7588093 | 0.87 | CYP1A2 (0.64) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL20417368 | 0.87 | CYP1A2 (0.64) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL8922442 | 0.86 | PRSS1 (0.47) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL8924985 | 0.86 | PRSS1 (0.47) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL26946426 | 0.85 | CYP1A2 (0.61) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL20824974 | 0.85 | CYP1A2 (0.61) | CYP1A2DGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL7590365 | 0.82 | CYP1A2 (0.64) | CYP1A2DGKAHTR2CPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |