Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922673 | 0.90 | NR1I2 (0.62) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8925436 | 0.90 | NR1I2 (0.61) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8924152 | 0.88 | NR1I2 (0.64) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8924971 | 0.88 | NR1I2 (0.69) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8921893 | 0.87 | NR1I2 (0.65) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8922225 | 0.85 | NR1I2 (0.63) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8923477 | 0.82 | NR1I2 (0.64) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8926521 | 0.82 | NR1I2 (0.69) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8925641 | 0.81 | NR1I2 (0.64) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8924815 | 0.81 | NR1I2 (0.62) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |