Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24060912 | 0.84 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KDM4ETSHR | |
| SCHEMBL7293012 | 0.82 | KCNA5 (0.49) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 | |
| SCHEMBL8986648 | 0.82 | KCNA5 (0.49) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 | |
| SCHEMBL6575099 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KDM4ETSHR | |
| SCHEMBL4479123 | 0.81 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KDM4ETSHR | |
| SCHEMBL1856673 | 0.81 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KDM4ETSHR | |
| SCHEMBL16227724 | 0.81 | KCNA5 (0.47) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 | |
| SCHEMBL6000906 | 0.81 | KCNA5 (0.47) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL8608055 | 0.81 | KCNA5 (0.47) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 | |
| SCHEMBL28331181 | 0.81 | KCNA5 (0.47) | SLC6A2SLC6A4KDM4ETSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |