Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 11/20 | 0.52 |
| ▸ | TOP2A | P11388 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888805 | 0.91 | MEN1 (0.57) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Hydrochloric Acid SCHEMBL8799597 | 0.90 | MEN1 (0.56) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10449186 | 0.89 | MEN1 (0.73) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Hydrochloric Acid SCHEMBL10581429 | 0.88 | MEN1 (0.72) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8554756 | 0.87 | MEN1 (0.61) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL6305453 | 0.86 | KCNH2 (0.73) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Hydrochloric Acid SCHEMBL10543998 | 0.85 | KCNH2 (0.72) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8557952 | 0.84 | MEN1 (0.58) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9688639 | 0.84 | GSK3B (0.60) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10547807 | 0.82 | KCNH2 (0.68) | MEN1KMT2AKCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672600-A | Antimicrobial dithiocarbamoyl quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5387748-A | Antimicrobial dithiocarbamoyl quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1990004591-A1 | NOVEL ANTIMICROBIAL DITHIOCARBAMOYL QUINOLONES | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-05-03 | — | — | WO | disclosed |
| EP-0366643-A2 | Novel antimicrobial dithiocarbamoyl quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |