SCHEMBL8923161

SCHEMBL8923161

O=C(O)c1ccc(C(c2ccc(C(=O)O)c(C(=O)O)c2)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F)cc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.41
CYP2C19 P33261 1/20 0.41
SORT1 Q99523 13/20 0.41
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
CES2 O00748 2/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920312 0.95 HSD17B10 (0.46) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL29441324 0.89 HSD17B10 (0.50) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL29401067 0.89 HSD17B10 (0.50) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL9492931 0.89 HSD17B10 (0.50) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL1770132 0.89 HSD17B10 (0.50) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL109108 0.89 HSD17B10 (0.50) HSD17B10KDM4EALDH1A1HPGDTDP1
Hydrochloric Acid SCHEMBL8507928 0.87 HSD17B10 (0.49) HSD17B10KDM4EALDH1A1HPGDTDP1
Water SCHEMBL4580188 0.87 HSD17B10 (0.49) HSD17B10KDM4EALDH1A1HPGDTDP1
Water SCHEMBL3223306 0.87 HSD17B10 (0.49) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL5549572 0.87 HSD17B10 (0.49) HSD17B10KDM4EALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670084-A Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed
EP-0708149-A1 Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-24 EP disclosed