Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | BCL2 | P10415 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | RPA1 | P27694 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642428 | 0.92 | CA9 (0.58) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL8922808 | 0.91 | CA9 (0.59) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL9201539 | 0.90 | CA9 (0.70) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL9206389 | 0.90 | CA9 (0.64) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL9201591 | 0.88 | CA9 (0.61) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL9200872 | 0.88 | CHRNA7 (0.71) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL9202688 | 0.88 | CHRNA7 (0.71) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL7467365 | 0.87 | CA9 (0.58) | CA9CHRNA7FAAHBCL2MDM2 | |
| Hydrochloric Acid SCHEMBL9209971 | 0.86 | CA9 (0.56) | CA9CHRNA7FAAHBCL2MDM2 | |
| SCHEMBL8922991 | 0.85 | CA9 (0.56) | CA9CHRNA7FAAHBCL2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |