Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996951 | 0.82 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL11424416 | 0.82 | NPC1 (0.93) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL1578277 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL11433155 | 0.79 | NPC1 (0.93) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL13996944 | 0.78 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL2836336 | 0.78 | BCHE (0.69) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4500939 | 0.77 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL15646615 | 0.76 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL1578589 | 0.76 | KMT2A (0.95) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL8975296 | 0.75 | BCHE (0.72) | NPC1SMN1; SMN2HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9249648-A | — | — | None | — | — | JP | disclosed |
| JP-H09249648-A | 2,6-DICHLOROISONICOTINIC ACID PHENOXYALKYLAMIDE DERIVATIVE AND AGROCHEMICAL | DAINIPPON INK & CHEM INC | 1997-09-22 | — | — | JP | disclosed |