Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6196997 | 0.79 | PDE4A (0.55) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6199824 | 0.77 | PDE4A (0.61) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL9413051 | 0.77 | PDE4A (0.60) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL8923403 | 0.76 | PDE4A (0.62) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8924868 | 0.76 | PDE4A (0.59) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL8925279 | 0.75 | PDE4A (0.61) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL6194685 | 0.75 | PDE4A (0.66) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8924567 | 0.74 | PDE4A (0.60) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL8922604 | 0.74 | PDE4A (0.50) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6202837 | 0.74 | SREBF2 (0.60) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |