Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8923909

CC(N)CCNCCCCNC(=O)NCC(=O)NCCCCCCNC(=N)N.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 3/20 0.37
NPY1R P25929 2/20 0.36
HDAC3 O15379 4/20 0.34
HDAC4 P56524 4/20 0.34
HDAC1 Q13547 4/20 0.34
HDAC7 Q8WUI4 4/20 0.34
HDAC2 Q92769 4/20 0.34
HDAC10 Q969S8 4/20 0.34
HDAC11 Q96DB2 4/20 0.34
HDAC8 Q9BY41 4/20 0.34
HDAC6 Q9UBN7 4/20 0.34
HDAC9 Q9UKV0 4/20 0.34
HDAC5 Q9UQL6 4/20 0.34
S1PR1 P21453 4/20 0.34
S1PR3 Q99500 4/20 0.34
S1PR2 O95136 3/20 0.34
S1PR5 Q9H228 3/20 0.34
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15124102 0.92 EPHX1 (0.35) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL524546 0.92 EPHX1 (0.35) HDAC3HDAC4HDAC1HDAC7HDAC2
Trifluoroacetic Acid SCHEMBL8919832 0.90 NPY4R (0.39) NPY4RHDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL8919616 0.90 NPY4R (0.39) NPY4RHDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL8921920 0.90 NPY4R (0.39) NPY4RHDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL8920249 0.86 NPY4R (0.38) NPY4RNPY1RHDAC3HDAC4HDAC1
Trifluoroacetic Acid SCHEMBL8921713 0.86 NPY4R (0.38) NPY4RNPY1RHDAC3HDAC4HDAC1
Trifluoroacetic Acid SCHEMBL9179852 0.85 HDAC6 (0.45) NPY4RHDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL9172174 0.85 HDAC6 (0.45) NPY4RHDAC3HDAC4HDAC1HDAC7
Trifluoroacetic Acid SCHEMBL8923917 0.83 NPY1R (0.36) NPY1RHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637613-A ANTITUMOR AGENT; IMMUNOSUPPRESSANTS FOURNIER INDUSTRIE ET SANTE (FR) 1997-06-10 US disclosed