Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382893 | 1.00 | PLA2G4B (0.52) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL4270500 | 1.00 | PLA2G4B (0.52) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7167527 | 0.95 | PLA2G4B (0.53) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL8926782 | 0.95 | PLA2G4B (0.53) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL1877602 | 0.93 | PLA2G4B (0.46) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7171414 | 0.93 | PLA2G4B (0.44) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3273651 | 0.92 | PLA2G4B (0.48) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL4276574 | 0.91 | PLA2G4B (0.45) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3272113 | 0.91 | PLA2G4B (0.45) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL8924946 | 0.91 | PLA2G4B (0.54) | PLA2G4BLMNANPC1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637256-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1992020058-A2 | FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS | UNIVERSITY RESEARCH CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |