Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25272332 | 0.79 | KMT2A (0.46) | KMT2ASMN1; SMN2HSD11B1ALDH1A1HPGD | |
| SCHEMBL21723552 | 0.78 | KMT2A (0.46) | KMT2ASMN1; SMN2HSD11B1ALDH1A1HPGD | |
| SCHEMBL21723551 | 0.78 | KMT2A (0.46) | KMT2ASMN1; SMN2HSD11B1ALDH1A1HPGD | |
| SCHEMBL2638702 | 0.75 | ELANE (0.49) | HSD11B1OGFRL1KDM4EPOLBTDP1 | |
| SCHEMBL2638698 | 0.75 | ELANE (0.49) | HSD11B1OGFRL1KDM4EPOLBTDP1 | |
| SCHEMBL25228050 | 0.75 | SPHK1 (0.44) | KMT2ASMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29220879 | 0.74 | KMT2A (0.54) | KMT2ASMN1; SMN2HSD11B1 | |
| SCHEMBL29220881 | 0.74 | KMT2A (0.54) | KMT2ASMN1; SMN2HSD11B1 | |
| SCHEMBL21853236 | 0.72 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21853250 | 0.72 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |