Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049499 | 1.00 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL5348258 | 1.00 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL8926785 | 1.00 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL9051114 | 1.00 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL5307937 | 0.84 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL5304265 | 0.84 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL30510969 | 0.84 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL3177611 | 0.84 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL3177621 | 0.84 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3KCNH2MLNR | |
| SCHEMBL3177626 | 0.84 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3KCNH2MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614518-A | Morpholine derivatives as dopamine receptor subtype ligands | MERCK SHARP & DOHME LTD. (GB) | 1997-03-25 | — | — | US | disclosed |