Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768665 | 0.96 | PPARA (0.47) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768126 | 0.90 | PPARA (0.46) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768890 | 0.89 | PPARA (0.53) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768641 | 0.88 | PPARA (0.51) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768990 | 0.87 | PPARA (0.50) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8767760 | 0.83 | PPARA (0.48) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768902 | 0.83 | PPARA (0.48) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768649 | 0.83 | PPARA (0.48) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8769015 | 0.83 | PPARA (0.49) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768932 | 0.82 | HDAC6 (0.50) | PPARAPPARGPPARDSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0639178-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS. | WELLCOME FOUND (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992010468-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-25 | — | — | WO | disclosed |