SCHEMBL8925475

SCHEMBL8925475

[N-]=[N+]=C1C=C(C(=O)O)C(Nc2ccccc2)=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2K7 O14733 1/20 0.34
CDC25B P30305 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CASP3 P42574 2/20 0.33
SENP7 Q9BQF6 2/20 0.33
FABP4 P15090 1/20 0.33
RHOA P61586 1/20 0.33
MAPT P10636 9/20 0.33
GAA P10253 3/20 0.33
NPC1 O15118 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632663 0.78 NPC1 (0.31) MEN1KMT2ACASP3SENP7MAPT
SCHEMBL9634644 0.75
SCHEMBL9633633 0.75 SRC (0.34) ALDH1A1HPGD
SCHEMBL9633545 0.71 S1PR2 (0.36)
SCHEMBL9632677 0.70
SCHEMBL15645533 0.69
SCHEMBL4777335 0.68
SCHEMBL3080719 0.66 HSD17B10 (0.37) MEN1KMT2AMAPTGAAHTT
SCHEMBL11539446 0.63 HSD17B10 (0.46) MEN1KMT2ACASP3SENP7MAPT
SCHEMBL9634334 0.61 HSD17B10 (0.31) L3MBTL1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637435-A CONTAINING UPPER AND LOWER PHOTOSENSITIVE LAYERS ON SUPPORT HAVING HYDROPHILIC SURFACE, UPPER LAYER OF ORGANIC SOLVENT-SOLUBLE DIAZO RESIN AND LOWER LAYER OF WATER-SOLUBLE DIAZO RESIN OF SPECIFIED CONCENTRATIONS AND THICKNESSES MITSUBISHI CHEMICAL CORPORATION (JP) 1997-06-10 US disclosed