Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.67 |
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924291 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8924280 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8925459 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8925761 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL9428216 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8926259 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL9457142 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8925529 | 1.00 | KCNH2 (0.67) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8923810 | 0.90 | DPP4 (0.58) | KCNH2DPP4CHRM2DRD1KMT2A | |
| SCHEMBL8925490 | 0.90 | DPP4 (0.58) | KCNH2DPP4CHRM2DRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633264-A | Individual stereoisomers of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-Quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5563155-A | QUINOLONE ANTIBIOTICS WITH INCREASED EFFICACY, REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5461165-A | Individual stereoisomers of intermediates of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5344940-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1994-09-06 | — | — | US | disclosed |