Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22367640 | 0.82 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL8925055 | 0.81 | ACE2 (0.46) | MAPTALDH1A1 | |
| SCHEMBL12023698 | 0.79 | ABCC4 (0.44) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL7334425 | 0.78 | OR51E2 (0.33) | TSHR | |
| SCHEMBL22367755 | 0.77 | MAPT (0.45) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL2805648 | 0.76 | MAPT (0.43) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL29954548 | 0.76 | BLM (0.50) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL12113872 | 0.76 | BLM (0.50) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL22367767 | 0.76 | MAPT (0.39) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL3109520 | 0.76 | BLM (0.50) | MAPTABCC4ALDH1A1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599960-A | UNSATURATED ESTERS AS INTERMEDIATES FOR FURANONE ORGANOLEPTICS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1997-02-04 | — | — | US | disclosed |
| US-5583237-A | CATALYTICALLY REACTING 2,7-OCTADIENOL/1-/ WITH TRIALKYL ORTHOPROPIONATE IN PRESENCE OF LEWIS ACID YIELDS ALKYL ESTER WHICH IS SAPONIFIED, HYDROLYZED AND DISTILLED, THEN LACTONIZATION AND ISOLATION | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1996-12-10 | — | — | US | disclosed |