Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926681 | 1.00 | TACR1 (0.59) | TACR1TACR3 | |
| SCHEMBL8924649 | 0.89 | TACR1 (0.58) | TACR1TACR3 | |
| SCHEMBL8924656 | 0.89 | TACR1 (0.58) | TACR1TACR3 | |
| SCHEMBL8502429 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8923727 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL7862639 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8923736 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL7862635 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8925793 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8300981 | 0.84 | TACR1 (0.81) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646144-A | FOR TREATING DISORDERS IN WHICH SUBSTANCE P PLAYS A PART IN DEVELOPMENT | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5541195-A | SUBSTANCE P ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0532456-B1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| US-5310743-A | Substance P antagonist | CIBA-GEIGY CORP. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0532456-A1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |