⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975449 | 0.88 | — | — | |
| SCHEMBL1485741 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL176077 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL7561906 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL7561639 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL7421378 | 0.82 | — | — | |
| SCHEMBL2995744 | 0.82 | — | — | |
| SCHEMBL9985571 | 0.82 | — | — | |
| SCHEMBL3210869 | 0.78 | ESR1 (0.30) | — | |
| SCHEMBL20198621 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-112513020-A | KDM1A inhibitors for the treatment of disease | 伊美格生物科学公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0747348-A1 | AMINOALKYLCYCLOPROPANE DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1996-12-11 | — | — | EP | disclosed |
| EP-0747348-A1 | AMINOALKYLCYCLOPROPANE DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-4194008-A | INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |