SCHEMBL8926799

SCHEMBL8926799

Cc1cn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O.Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.78

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 4/20 0.78
POLB P06746 3/20 0.58
POLA1 P09884 1/20 0.55
POLD1 P28340 1/20 0.55
ENPP1 P22413 3/20 0.54
P2RY1 P47900 3/20 0.54
TERT O14746 2/20 0.53
P2RX1 P51575 1/20 0.52
P2RX3 P56373 1/20 0.52
P2RX2 Q9UBL9 1/20 0.52
P2RY2 P41231 1/20 0.50
P2RY4 P51582 1/20 0.50
P2RY6 Q15077 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9160842 0.91 DTYMK (0.83) DTYMKPOLBENPP1P2RY1TERT
Deoxyadenosine SCHEMBL3817507 0.91 DTYMK (0.85) DTYMKP2RY1P2RX1P2RX3P2RX2
Deoxyguanosine Triphosphate SCHEMBL3677443 0.89 POLB (0.63) DTYMKPOLBPOLA1POLD1TERT
SCHEMBL13421167 0.88 DTYMK (1.00) DTYMKP2RY1P2RX1P2RX3P2RX2
SCHEMBL16480319 0.88 DTYMK (1.00) DTYMKP2RY1P2RX1P2RX3P2RX2
SCHEMBL12548879 0.88 DTYMK (1.00) DTYMKP2RY1P2RX1P2RX3P2RX2
SCHEMBL31061664 0.88 DTYMK (1.00) DTYMKP2RY1P2RX1P2RX3P2RX2
SCHEMBL26031192 0.88 DTYMK (1.00) DTYMKP2RY1P2RX1P2RX3P2RX2
Adenosine SCHEMBL3194871 0.88 DTYMK (0.91) DTYMKP2RY1P2RX1P2RX3P2RX2
SCHEMBL5852678 0.87 DTYMK (0.63) DTYMKTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656461-A GENETIC ENGINEERING GENETICS & IVF INSTITUTE, INC. (US) 1997-08-12 US disclosed
US-5629178-A Method for enhancing amplification in the polymerase chain reaction employing peptide nucleic acid (PNA) GENETICS & IVF INSTITUTE (US) 1997-05-13 US disclosed
WO-1996013611-A9 A METHOD FOR ENHANCING AMPLIFICATION IN THE POLYMERASE CHAIN REACTION EMPLOYING PEPTIDE NUCLEIC ACID (PNA) 1996-07-18 WO disclosed
WO-1996013611-A1 A METHOD FOR ENHANCING AMPLIFICATION IN THE POLYMERASE CHAIN REACTION EMPLOYING PEPTIDE NUCLEIC ACID (PNA) GENETICS & IVF INSTITUTE, INC. (US) 1996-05-09 WO disclosed