SCHEMBL8927245

SCHEMBL8927245

C=C(C)C(=O)OC(CCCCC)CCO[SiH](OCCCCCCCC)OCCCCCCCC

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
CES2 O00748 1/20 0.34
FAAH O00519 1/20 0.34
PLA2G2C Q5R387 2/20 0.33
ZDHHC7 Q9NXF8 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
GPR84 Q9NQS5 3/20 0.32
NAAA Q02083 1/20 0.32
FFAR1 O14842 1/20 0.32
GLS2 Q9UI32 3/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164433 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL21647274 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL2725427 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL1702704 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL886833 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL6679717 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL478186 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL21853813 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL21853809 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1
SCHEMBL11775442 0.85 TSHR (0.55) TSHRFAAHZDHHC7MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616753-A Stabilizers for unsaturated, polymerizable organosilicon compounds OSI SPECIALTIES, INC. (US) 1997-04-01 US claimed
US-5616753-A Stabilizers for unsaturated, polymerizable organosilicon compounds OSI SPECIALTIES, INC. (US) 1997-04-01 US disclosed