Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192003 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL8927034 | 0.79 | — | — | |
| SCHEMBL4201014 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10715344 | 0.76 | USP2 (0.32) | ALDH1A1POLB | |
| SCHEMBL3280462 | 0.76 | NR5A2 (0.30) | — | |
| SCHEMBL373554 | 0.74 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9323473 | 0.74 | HSPA5 (0.35) | ALDH1A1HSPA5CYP2C9CYP2C19HIF1A | |
| SCHEMBL29353402 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29445825 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29865276 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670284-A | HAVING CHARGE GENERATING LAYER COMPRISING POLYALKYLENE GLYCOL AND/OR ESTER OR ETHER THEREOF AND/OR CROWN ETHER, CHARGE TRANSPORT LAYER COMPRISING ANTIOXIDANT | RICOH COMPANY, LTD. (JP) | 1997-09-23 | — | — | US | disclosed |