SCHEMBL8927478

SCHEMBL8927478

C[C@H]1C(N)CCCN1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 12/20 0.39
DPP7 Q9UHL4 10/20 0.39
FAP Q12884 8/20 0.39
DPP8 Q6V1X1 7/20 0.39
DPP9 Q86TI2 6/20 0.39
PREP P48147 5/20 0.39
ACE P12821 4/20 0.37
REN P00797 2/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 2/20 0.37
PITRM1 Q5JRX3 1/20 0.37
CYP2C19 P33261 1/20 0.37
KDM4E B2RXH2 1/20 0.37
F2 P00734 1/20 0.37
LTA4H P09960 1/20 0.37
MAPT P10636 1/20 0.37
PEPD P12955 1/20 0.37
ALOX15 P16050 1/20 0.37
PTGS1 P23219 1/20 0.37
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18283815 1.00 DPP4 (0.39) DPP4DPP7FAPDPP8DPP9
SCHEMBL4059132 1.00 DPP4 (0.39) DPP4DPP7FAPDPP8DPP9
Hydrochloric Acid SCHEMBL3487428 0.98 DPP4 (0.38) DPP4DPP7FAPDPP8DPP9
SCHEMBL22469047 0.94 HPGD (0.40) DPP4DPP7FAPDPP8DPP9
SCHEMBL25299858 0.88 GABRR1 (0.31) DPP4DPP7FAPDPP8DPP9
SCHEMBL19252608 0.88 GABRR1 (0.31) DPP4DPP7FAPDPP8DPP9
SCHEMBL12491953 0.88 GABRR1 (0.31) DPP4DPP7FAPDPP8DPP9
SCHEMBL13651247 0.88 GABRR1 (0.31) DPP4DPP7FAPDPP8DPP9
SCHEMBL10002337 0.79 POLB (0.36) DPP4DPP7FAPDPP8DPP9
SCHEMBL4775884 0.78 DPP4 (0.36) DPP4DPP7FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677448-A CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS HOFFMANN-LA ROCHE INC. (US) 1997-10-14 US disclosed
US-5393760-A Cardiovascular disorders, antitumor agents HOFFMANN-LA ROCHE INC. (US) 1995-02-28 US disclosed