Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532922 | 0.93 | RARB (0.63) | RARBALDH1A1MAPTTP53TSHR | |
| SCHEMBL8082310 | 0.93 | RARB (0.63) | RARBALDH1A1MAPTTP53TSHR | |
| SCHEMBL8082284 | 0.93 | RARB (0.63) | RARBALDH1A1MAPTTP53TSHR | |
| SCHEMBL8194653 | 0.93 | RARB (0.63) | RARBALDH1A1MAPTTP53TSHR | |
| Hydrochloric Acid SCHEMBL10455057 | 0.92 | RARB (0.62) | RARBALDH1A1MAPTTP53TSHR | |
| SCHEMBL9477903 | 0.92 | RARB (0.61) | RARBALDH1A1MAPTTP53TSHR | |
| SCHEMBL9808804 | 0.92 | RARB (0.70) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL13953004 | 0.89 | TP53 (0.60) | RARBALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL5091731 | 0.89 | TP53 (0.60) | RARBALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL7691425 | 0.89 | TP53 (0.60) | RARBALDH1A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658493-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |