Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377601 | 0.82 | ESR1 (0.41) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL12744851 | 0.82 | ESR1 (0.41) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL13759588 | 0.78 | HMGCR (0.47) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL13030818 | 0.78 | HMGCR (0.47) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL14570394 | 0.78 | HMGCR (0.47) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL13324429 | 0.78 | — | — | |
| SCHEMBL16502168 | 0.78 | ESR1 (0.39) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL15440625 | 0.78 | ESR1 (0.39) | ESR1THRATHRBALDH1A1HPGD | |
| SCHEMBL12018819 | 0.76 | CHUK (0.32) | ESR1THRBALDH1A1HPGD | |
| SCHEMBL13201752 | 0.76 | HMGCR (0.42) | ESR1THRATHRBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188485-B2 | Detection system having a light emitting diode | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2012-05-29 | — | — | US | disclosed |
| US-7723711-B2 | Disposable optical sensor and method of manufacturing same | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOCK TNO (NL) | 2010-05-25 | — | — | US | disclosed |
| US-20070102654-A1 | Sensor comprising polymeric components | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-05-10 | — | — | US | disclosed |