Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.98 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.48 |
| ▸ | CDC25B | P30305 | 8/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928920 | 1.00 | NT5E (0.98) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL9164604 | 1.00 | NT5E (0.98) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL749253 | 0.99 | NT5E (1.00) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL6313490 | 0.99 | NT5E (1.00) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8184231 | 0.99 | NT5E (1.00) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL6313488 | 0.99 | NT5E (1.00) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8184232 | 0.99 | NT5E (1.00) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL11418140 | 0.97 | NT5E (0.93) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL11418144 | 0.97 | NT5E (0.93) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8998271 | 0.92 | NT5E (0.84) | NT5EPTPN1CDC25BPTPN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622936-A | COMPLEX OF SUGAR WITH A PHOSPHORUS AMIDE | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0369182-B1 | Antitumour saccharide conjugates | DEUTSCHES KREBSFORSCH (DE) | 1995-03-29 | — | — | EP | disclosed |
| EP-0369182-A1 | Antitumour saccharide conjugates | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1990-05-23 | — | — | EP | disclosed |
| WO-1990004597-A1 | TUMOR-INHIBITING SACCHARIDE CONJUGATES | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1990-05-03 | — | — | WO | disclosed |