SCHEMBL8928887

SCHEMBL8928887

C=Cc1cc(C=CC#N)ccc1C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.43
▸ FDPS P14324 1/20 0.42
▸ ENPP2 Q13822 1/20 0.39
▸ ESR1 P03372 1/20 0.32
▸ TUBB1 Q9H4B7 1/20 0.32
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ ABCG2 Q9UNQ0 1/20 0.31
▸ AKR1C3 P42330 1/20 0.30
▸ ALOX5 P09917 1/20 0.30
▸ PTGS1 P23219 1/20 0.30
▸ PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147276 0.80 KDM4E (0.50) KDM4EFDPSENPP2ESR1TUBB1
SCHEMBL5161207 0.80 KDM4E (0.50) KDM4EFDPSENPP2ESR1TUBB1
SCHEMBL29651844 0.77 TDP1 (0.46) KDM4EESR1TUBB1ALOX5PTGS1
SCHEMBL41439 0.77 TDP1 (0.46) KDM4EESR1TUBB1ALOX5PTGS1
SCHEMBL24668842 0.77 TTR (0.42) KDM4EFDPSENPP2TUBB1CYP1A2
SCHEMBL4015184 0.77 TUBB1 (0.34) TUBB1ALOX5PTGS1PTGS2
SCHEMBL18854463 0.77 KDM4E (0.47) KDM4EFDPSENPP2ESR1TUBB1
SCHEMBL18854461 0.77 KDM4E (0.47) KDM4EFDPSENPP2ESR1TUBB1
SCHEMBL19595030 0.75 KDM4E (0.46) KDM4EFDPSENPP2ESR1TUBB1
SCHEMBL1199056 0.75 TTR (0.47) KDM4ETUBB1CYP1A2ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2922923-A1 AN INTUMESCENT COATING COMPOSITION PPG Coatings Europe B.V. (NL) 2015-09-30 — — EP claimed
WO-2014080000-A1 AN INTUMESCENT COATING COMPOSITION PPG COATINGS EUROPE B.V. (NL) 2014-05-30 — — WO claimed
EP-0019660-A1 Pigmented printing paste DAINIPPON INK AND CHEMICALS, INC. (JP) 1980-12-10 — — EP claimed
US-20260055293-A1 COATING SYSTEM PPG Architectural Finishes, Inc. d/b/a The Pittsburgh Paints Co. (US) 2026-02-26 — — US disclosed
EP-4667538-A1 INTUMESCENT COATING COMPOSITION USING GLYCOURIL AND AMINOTRIAZINE COMPOUND AS BLOWING AGENT CLARIANT INTERNATIONAL LTD (CH) 2025-12-24 — — EP disclosed
US-12371584-B2 Coating system THE PITTSBURGH PAINTS CO. (US) 2025-07-29 — — US disclosed
US-12116501-B2 Configurable coating system CONSORCIO COMEX S.A. DE C.V. (MX) 2024-10-15 — — US disclosed
US-20240218190-A1 CONFIGURABLE COATING COMPOSITION CONSORCIO COMEX S.A. DE C.V. (MX) 2024-07-04 — — US disclosed
EP-3844225-B1 CONFIGURABLE COATING SYSTEM CONSORCIO COMEX S A DE C V (MX) 2024-03-06 — — EP disclosed
CN-114656854-A Coating composition PPG涂料欧洲有限责任公司 2022-06-24 — — CN disclosed
US-20220119647-A1 Configurable Coating System Corsorcio Comex S.A. de C.V. (MX) 2022-04-21 — — US disclosed
EP-3140353-A1 A COATING COMPOSITION PPG Coatings Europe B.V. (NL) 2017-03-15 — — EP disclosed
WO-2015169806-A1 A COATING COMPOSITION PPG COATINGS EUROPE B.V. (NL) 2015-11-12 — — WO disclosed
EP-2942374-A1 A Coating Composition PPG Coatings Europe B.V. (NL) 2015-11-11 — — EP disclosed
US-20150291810-A1 Intumescent Coating Composition PPG COATINGS EUROPE B.V. 2015-10-15 — — US disclosed
EP-2922923-A1 AN INTUMESCENT COATING COMPOSITION PPG Coatings Europe B.V. (NL) 2015-09-30 — — EP disclosed
WO-2014080000-A1 AN INTUMESCENT COATING COMPOSITION PPG COATINGS EUROPE B.V. (NL) 2014-05-30 — — WO disclosed
EP-0555471-B1 METHOD OF OBTAINING POLYSTYRENE PLASTICS OKHTINSKOE N PROIZV OBIENINENI (RU) 1997-01-29 — — EP disclosed
US-5464915-A Calcium triphosphate stabilizers for addition polymerization PLASTPOLYMER SHARE HOLDING COMPANY (RU) 1995-11-07 — — US disclosed
EP-0555471-A1 METHOD OF OBTAINING POLYSTYRENE PLASTICS OKHTINSKOE NAUCHNO-PROIZVODSTVENNOE OBIENINENIE "PLASTOPOLIMER" (SU) 1993-08-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055293-A1 COATING SYSTEM STRA6, LCP1, CSTB KDM4E 3924/4885FDPS 4074/4885ENPP2 4567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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