Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140465 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL2141366 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL183389 | 0.75 | SMPD1 (0.34) | PGK1PGK2CA12CA1CA2 | |
| SCHEMBL9037414 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28328876 | 0.73 | SMPD1 (0.33) | PGK1PGK2CA12CA1CA2 | |
| SCHEMBL28406935 | 0.70 | — | — | |
| SCHEMBL1662031 | 0.70 | — | — | |
| SCHEMBL10523418 | 0.69 | — | — | |
| SCHEMBL27912661 | 0.68 | CA12 (0.31) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL29161242 | 0.67 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605795-A | Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor | TROPIX, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5220005-A | Reactable with enzyme to release optically detectable energy | TROPIX, INC. (US) | 1993-06-15 | — | — | US | disclosed |