Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | DDO | Q99489 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280341 | 0.87 | KDM4E (0.56) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL1037203 | 0.85 | KDM4E (0.72) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL19952775 | 0.85 | KDM4E (0.69) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL29612172 | 0.85 | KDM4E (0.69) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL8930303 | 0.83 | DAO (0.60) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL12277477 | 0.82 | KDM4E (0.58) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL1621884 | 0.81 | KDM4E (0.68) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL1228041 | 0.81 | KDM4E (0.62) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12245172 | 0.81 | DAO (0.57) | DAODDOKDM4ETDP1MEN1 | |
| SCHEMBL14767763 | 0.81 | KDM4E (0.71) | DAODDOKDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032580-A1 | 3-SUBSTITUTED-4-OXA-1-AZABICYCLO[3,2,0]HEPTAN-7-ONE AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1997-09-12 | — | — | WO | disclosed |