Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933558 | 0.92 | CA1 (0.62) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL1933560 | 0.92 | CA1 (0.62) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL7294877 | 0.92 | CA1 (0.62) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL6279106 | 0.84 | CA1 (0.57) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL1566002 | 0.81 | CA1 (0.60) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL31208336 | 0.81 | CA1 (0.51) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL18653600 | 0.81 | CA1 (0.60) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL3348805 | 0.79 | CA1 (0.58) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL5153374 | 0.79 | CA1 (0.58) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL1975300 | 0.79 | CA1 (0.46) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577040-B1 | Process for the preparation of (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxy-hexanoic acid, tert.-butyl ester | HOECHST AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| US-5399722-A | Process for preparing tert-butyl (3R,5S)-6-hydroxy-3,5--O--isopropylidene-3,5-dihydroxyhexanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0577040-A2 | Process for the preparation of (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxy-hexanoic acid, tert.-butyl ester | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |