Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | CYP8B1 | Q9UNU6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548018 | 0.89 | MAPT (1.00) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL9284781 | 0.89 | MAPT (1.00) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL3120176 | 0.89 | MAPT (1.00) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL19738655 | 0.88 | MAPT (0.81) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL19172887 | 0.86 | MAPT (0.78) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL23678506 | 0.85 | MAPT (0.80) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL12240584 | 0.85 | MAPT (0.80) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL23355483 | 0.85 | MAPT (0.80) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL19730460 | 0.85 | MAPT (0.80) | MAPTLMNAKDM4EALDH1A1GAA | |
| SCHEMBL16975619 | 0.85 | MAPT (0.80) | MAPTLMNAKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764641-A1 | NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-26 | — | — | EP | claimed |
| EP-0764641-A1 | NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-26 | — | — | EP | disclosed |