⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443171 | 1.00 | — | — | |
| SCHEMBL7024358 | 0.71 | — | — | |
| SCHEMBL17113664 | 0.69 | — | — | |
| SCHEMBL92616 | 0.69 | — | — | |
| SCHEMBL13663738 | 0.69 | — | — | |
| SCHEMBL21142641 | 0.67 | — | — | |
| SCHEMBL14573053 | 0.67 | CARM1 (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL12500116 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2713997 | 0.67 | — | — | |
| SCHEMBL7024359 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024116207-A1 | ADAR1 INHIBITORS AND METHODS OF USING THE SAME | AVAMMUNE THERAPEUTICS INC. (IN) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20180051042-A1 | METHODS FOR FORMING SATURATED (HETERO)CYCLIC BORYLATED HYDROCARBONS AND RELATED COMPOUNDS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2018-02-22 | — | — | US | disclosed |
| US-20150361087-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-17 | — | — | US | disclosed |
| US-20150353529-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-10 | — | — | US | disclosed |
| US-9156823-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2015-10-13 | — | — | US | disclosed |
| US-20140018313-A1 | ANTIVIRAL COMPOUNDS | Gelead Sciences, Inc. | 2014-01-16 | — | — | US | disclosed |
| US-8188037-B2 | Microparticles comprising somatostatin analogues | NOVARTIS AG (CH) | 2012-05-29 | — | — | US | disclosed |