Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15583777 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL269561 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20594558 | 0.90 | TP53 (0.48) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL9513316 | 0.90 | TP53 (0.48) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL24158118 | 0.89 | PRSS1 (0.49) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL12154333 | 0.89 | PRSS1 (0.49) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL21096571 | 0.89 | PRSS1 (0.49) | SMN1; SMN2KMT2AMAPTPRSS1ACR | |
| SCHEMBL11600892 | 0.89 | MAPT (0.60) | SMN1; SMN2KMT2AMAPTPRSS1CA1 | |
| SCHEMBL18328861 | 0.87 | TP53 (0.49) | SMN1; SMN2LMNAKMT2AMAPTPRSS1 | |
| SCHEMBL11598712 | 0.87 | MAPT (0.44) | SMN1; SMN2KMT2AMAPTPRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5690857-A | LIQUID CRYSTAL ENCAPSULATED AND COATED WITH A METAL OXIDE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-11-25 | — | — | US | disclosed |
| EP-0617730-B1 | THERMOCHROMIC EFFECT PIGMENT AND PROCESS FOR PRODUCING THE SAME | MERCK PATENT GMBH (DE) | 1996-02-14 | — | — | EP | disclosed |