Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108329 | 1.00 | POLB (1.00) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL31265114 | 1.00 | POLB (1.00) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL3215221 | 0.84 | POLB (0.70) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL393414 | 0.84 | POLB (0.70) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL3200631 | 0.84 | POLB (0.70) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL8760765 | 0.84 | POLB (0.70) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL389507 | 0.84 | POLB (0.70) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL21878910 | 0.83 | POLB (0.71) | POLBTDP1PKMNPSR1TP53 | |
| SCHEMBL106105 | 0.80 | POLB (0.65) | POLBTDP1PKMNPSR1TP53 | |
| Hydrochloric Acid SCHEMBL9569081 | 0.77 | POLB (0.62) | POLBTDP1PKMNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623086-B1 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| US-9079828-B2 | Polymerizable compounds comprising a polyalicylic structure element | VOCO GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| EP-2623086-A2 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| EP-2436668-B1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GMBH (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-2436668-A1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GmbH (DE) | 2012-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | PCBP1, PUF60, PARG | POLB 160/4885TDP1 1169/4885PKM 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.