Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 16/20 | 1.00 |
| ▸ | SRD5A1 | P18405 | 16/20 | 1.00 |
| ▸ | FNTA | P49354 | 2/20 | 0.55 |
| ▸ | FNTB | P49356 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917095 | 1.00 | SRD5A2 (1.00) | SRD5A2SRD5A1FNTAFNTB | |
| SCHEMBL917094 | 1.00 | SRD5A2 (1.00) | SRD5A2SRD5A1FNTAFNTB | |
| SCHEMBL917215 | 0.93 | SRD5A2 (1.00) | SRD5A2SRD5A1FNTAFNTB | |
| SCHEMBL917213 | 0.93 | SRD5A2 (1.00) | SRD5A2SRD5A1FNTAFNTB | |
| SCHEMBL8333306 | 0.93 | SRD5A2 (1.00) | SRD5A2SRD5A1FNTAFNTB | |
| SCHEMBL918268 | 0.92 | SRD5A1 (0.86) | SRD5A2SRD5A1 | |
| SCHEMBL8931520 | 0.92 | SRD5A1 (0.86) | SRD5A2SRD5A1 | |
| SCHEMBL918267 | 0.92 | SRD5A1 (0.86) | SRD5A2SRD5A1 | |
| SCHEMBL916372 | 0.91 | SRD5A1 (0.84) | SRD5A2SRD5A1 | |
| SCHEMBL917238 | 0.91 | SRD5A2 (0.84) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572165-A1 | New 7B-substituted-4-aza-5a-cholestan-ones as 5a-reductase inhibitors | MERCK & CO. INC. (US) | 1993-12-01 | — | — | EP | claimed |
| WO-1993023419-A1 | NEW 7β-SUBSTITUTED-4-AZA-5α-CHOLESTAN-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| EP-0572165-B1 | New 7B-substituted-4-aza-5a-cholestan-ones as 5a-reductase inhibitors | MERCK & CO INC (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5527807-A | TREATING ALOPECIA, ACNE, PROSTATE DISORDERS | MERCK & CO., INC. (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0572165-A1 | New 7B-substituted-4-aza-5a-cholestan-ones as 5a-reductase inhibitors | MERCK & CO. INC. (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1993023419-A1 | NEW 7β-SUBSTITUTED-4-AZA-5α-CHOLESTAN-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |