Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.51 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.51 |
| ▸ | KYNU | Q16719 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341151 | 0.80 | SLC7A5 (0.62) | GRM2GRM3SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL27170852 | 0.80 | SLC7A5 (0.62) | GRM2GRM3SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL8530260 | 0.79 | SLC1A1 (0.56) | SLC1A2SLC1A1SLC1A3GRIK1ANPEP | |
| SCHEMBL11148099 | 0.78 | TSHR (0.53) | GRM2GRM3SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL28951586 | 0.76 | SLC1A1 (0.50) | GRM2GRM3SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18886173 | 0.76 | GRM2 (0.61) | GRM2GRM3KYNUSLC1A2SLC1A1 | |
| SCHEMBL5924823 | 0.76 | GRM2 (0.61) | GRM2GRM3KYNUSLC1A2SLC1A1 | |
| SCHEMBL5924700 | 0.76 | GRM2 (0.61) | GRM2GRM3KYNUSLC1A2SLC1A1 | |
| SCHEMBL6255681 | 0.76 | GRM2 (0.61) | GRM2GRM3KYNUSLC1A2SLC1A1 | |
| SCHEMBL5325189 | 0.76 | GRM2 (0.61) | GRM2GRM3KYNUSLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775210-A1 | MUTATED PENICILLIN G ACYLASE GENES | GIST-BROCADES B.V. (NL) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005318-A1 | MUTATED PENICILLIN G ACYLASE GENES | GIST-BROCADES B.V. (NL) | 1996-02-22 | — | — | WO | disclosed |