Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59050 | 1.00 | TUBB1 (0.52) | TUBB1PDF | |
| SCHEMBL14210202 | 0.91 | TUBB1 (0.54) | TUBB1PDF | |
| SCHEMBL58626 | 0.91 | TUBB1 (0.54) | TUBB1PDF | |
| SCHEMBL58912 | 0.88 | TUBB1 (0.42) | TUBB1 | |
| SCHEMBL59232 | 0.88 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL58392 | 0.85 | TUBB1 (0.51) | TUBB1 | |
| SCHEMBL58200 | 0.84 | TUBB1 (0.58) | TUBB1 | |
| SCHEMBL59655 | 0.83 | TUBB1 (0.53) | TUBB1PDF | |
| SCHEMBL58284 | 0.83 | TUBB1 (0.51) | TUBB1PDF | |
| SCHEMBL57850 | 0.82 | TUBB1 (0.58) | TUBB1PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374454-A1 | Hemiasterlin derivatives and uses thereof in the treatment of cancer | Eisai R&D Management Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |