Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227592 | 0.84 | MIF (0.52) | MIFNOS3NOS2LMNAESR1 | |
| SCHEMBL3927365 | 0.82 | MIF (0.40) | MIFNOS3NOS2HDAC8LMNA | |
| SCHEMBL23527635 | 0.81 | MIF (0.46) | MIFNOS3NOS2LMNACYP1A2 | |
| SCHEMBL21259586 | 0.81 | MIF (0.46) | MIFNOS3NOS2LMNACYP1A2 | |
| SCHEMBL5411169 | 0.78 | MIF (0.35) | MIFNOS2 | |
| SCHEMBL10341453 | 0.76 | MIF (0.44) | MIFNOS3NOS2 | |
| SCHEMBL21259575 | 0.76 | MIF (0.44) | MIFLMNAMAPTTDP1 | |
| SCHEMBL6194699 | 0.76 | MIF (0.44) | MIFLMNASLC6A2SLC6A3TDP1 | |
| SCHEMBL959016 | 0.76 | MIF (0.44) | MIFCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23527546 | 0.76 | MIF (0.44) | MIFLMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489699-A | USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND | ELFATOCHEM NORTH AMERICA, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5399630-A | Process for curing polymers using amino or hydrazino peroxides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-03-21 | — | — | US | disclosed |