Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38894 | 0.85 | ESR1 (0.46) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL29238209 | 0.80 | ESR1 (0.41) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL29238161 | 0.80 | ESR1 (0.41) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL26379080 | 0.74 | ESR2 (0.49) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL2903276 | 0.73 | KDM4E (0.55) | ESR1ESR2NR3C1PGRNR3C2 | |
| SCHEMBL38096 | 0.73 | KDM4E (0.55) | ESR1ESR2NR3C1PGRNR3C2 | |
| SCHEMBL2177581 | 0.73 | KDM4E (0.55) | ESR1ESR2NR3C1PGRNR3C2 | |
| SCHEMBL27798365 | 0.71 | ESR2 (0.46) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL18265442 | 0.71 | ESR1 (0.56) | ESR1ESR2OPRM1NR3C1PGR | |
| SCHEMBL4222808 | 0.68 | ESR2 (0.56) | ESR1ESR2NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023813-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO SH2 DOMAINS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-08-08 | — | — | WO | disclosed |