Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933209 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933282 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933352 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933281 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933260 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933091 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933280 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933388 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933178 | 0.99 | RARB (0.35) | PPARDCYP3A4CYP2C9FPR2RARB | |
| SCHEMBL8933072 | 0.98 | PPARD (0.35) | PPARDCYP3A4CYP2C9FPR2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |