SCHEMBL8933369

SCHEMBL8933369

C/C=C/C1CCC(c2ccc(-c3ccc(-c4ccc(CCCCCC)c(F)c4F)cc3)c(F)c2)CC1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.37
SPHK1 Q9NYA1 13/20 0.34
FASN P49327 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
APP P05067 1/20 0.31
SPHK2 Q9NRA0 7/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8933582 1.00 RARB (0.37) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8933578 1.00 RARB (0.37) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8933656 1.00 RARB (0.37) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8933610 1.00 RARB (0.37) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8933540 0.99 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8959327 0.97 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8959328 0.97 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8959326 0.97 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8959320 0.97 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9
SCHEMBL8959323 0.97 RARB (0.35) RARBSPHK1FASNCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed