Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.78 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | CPA2 | P48052 | 1/20 | 0.56 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | FURIN | P09958 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801766 | 1.00 | GNPAT (0.78) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL29550453 | 1.00 | GNPAT (0.78) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL3801759 | 1.00 | GNPAT (0.78) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL29368954 | 1.00 | GNPAT (0.78) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL30698071 | 0.96 | GNPAT (0.80) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL31181171 | 0.93 | GNPAT (0.69) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL15862955 | 0.92 | GNPAT (0.67) | GNPATITGB3ITGA2BCPA1CPA2 | |
| SCHEMBL1711591 | 0.90 | GNPAT (0.63) | GNPATERAP2LNPEPCPB2ECE1 | |
| SCHEMBL1711765 | 0.90 | GNPAT (0.63) | GNPATERAP2LNPEPCPB2ECE1 | |
| SCHEMBL1711769 | 0.90 | GNPAT (0.63) | GNPATERAP2LNPEPCPB2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996027373-A1 | USE OF N-SUBSTITUTED L-PHENYLALANINE ESTERS FOR THE TREATMENT OF ECZEMA | STIEFEL LABORATORIES, INC. (US) | 1996-09-12 | — | — | WO | disclosed |