Pentachlorophenol

Pentachlorophenol

SCHEMBL8933902

CCCCCCOCCCCCC.OCCO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
MAPT P10636 2/20 0.57
HTT P42858 2/20 0.57
THRB P10828 1/20 0.57
TSHR P16473 3/20 0.47
HSD17B10 Q99714 3/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
HIF1A Q16665 1/20 0.43
USP2 O75604 2/20 0.42
CES1 P23141 1/20 0.41
CES2 O00748 2/20 0.40
LMNA P02545 4/20 0.38
ALDH1A1 P00352 3/20 0.38
NR5A1 Q13285 1/20 0.38
CYP3A4 P08684 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL4320916 1.00 MEN1 (0.57) MEN1KMT2AMAPTHTTTHRB
Pentachlorophenol SCHEMBL8933811 0.92 TSHR (0.56) MEN1KMT2AMAPTHTTTHRB
Cetostearyl Alcohol SCHEMBL5471038 0.82 TSHR (0.59) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL3042535 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL17393537 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL23391389 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL17393627 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL17393515 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL17393624 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB
Ethylene Glycol SCHEMBL126664 0.82 MEN1 (0.81) MEN1KMT2AMAPTHTTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996026911-A1 EXPLOSIVES USING GLYCOL STILL BOTTOMS AN/GEL INTERNATIONAL (US) 1996-09-06 WO claimed
US-5531843-A INSTEAD OF FUEL OIL ICI EXPLOSIVES USA INC. 1996-07-02 US claimed