Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.32 |
| ▸ | HTR2A | P28223 | 6/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960692 | 0.97 | HTR2C (0.32) | HTR2CHTR2BOPRL1HTR2AFFAR4 | |
| SCHEMBL8961138 | 0.97 | HTR2C (0.31) | HTR2CHTR2BOPRL1HTR2AFFAR4 | |
| SCHEMBL8933980 | 0.94 | HTR2C (0.34) | HTR2CHTR2BOPRL1HTR2AFFAR4 | |
| SCHEMBL8960227 | 0.91 | HTR2C (0.33) | HTR2CHTR2BOPRL1HTR2AFFAR4 | |
| SCHEMBL8935665 | 0.91 | HTR2C (0.34) | HTR2CHTR2BHTR2AMEN1ALDH1A1 | |
| SCHEMBL8935564 | 0.91 | HTR2C (0.34) | HTR2CHTR2BHTR2AMEN1ALDH1A1 | |
| SCHEMBL8935430 | 0.91 | HTR2C (0.34) | HTR2CHTR2BHTR2AMEN1ALDH1A1 | |
| SCHEMBL8934124 | 0.91 | OPRL1 (0.34) | OPRL1FFAR4DGAT1 | |
| SCHEMBL8934342 | 0.90 | OPRL1 (0.34) | OPRL1FFAR4DGAT1 | |
| SCHEMBL8934128 | 0.90 | S1PR1 (0.35) | OPRL1FFAR4DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |