SCHEMBL8934172

SCHEMBL8934172

CCC/C=C\Oc1ccc(-c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3F)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
FASN P49327 1/20 0.32
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960407 0.97 FASN (0.31) CYP3A4CYP2C9FASN
SCHEMBL8934123 0.94 CYP3A4 (0.32) CYP3A4CYP2C9FASNAPP
SCHEMBL8960088 0.91 CYP3A4 (0.31) CYP3A4CYP2C9FASN
SCHEMBL8933768 0.91 CYP3A4 (0.33) CYP3A4CYP2C9FASNAPP
SCHEMBL8940845 0.89
SCHEMBL8960212 0.88 CYP3A4 (0.32) CYP3A4CYP2C9FASN
SCHEMBL19985444 0.88 CYP2C9 (0.33) CYP2C9
SCHEMBL15723066 0.87 CYP2C9 (0.39) CYP2C9
SCHEMBL8935969 0.87 GAA (0.32)
SCHEMBL19985463 0.87 MAPT (0.33) CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed