Carbamic Acid

Carbamic Acid

SCHEMBL8934191

CC(=O)OC[C@@H](CO)c1ccccn1.NC(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
CYP3A4 P08684 3/20 0.43
KDM4E B2RXH2 3/20 0.43
LMNA P02545 2/20 0.43
ABCB11 O95342 1/20 0.43
ESR1 P03372 1/20 0.43
ADRA2A P08913 1/20 0.43
CYP2C9 P11712 1/20 0.43
PDE4A P27815 1/20 0.43
ADRA1A P35348 1/20 0.43
OPRK1 P41145 1/20 0.43
STAT6 P42226 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HIF1A Q16665 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL8392051 1.00 TSHR (0.43) TSHRCYP3A4KDM4ELMNAABCB11
Carbamic Acid SCHEMBL8392049 1.00 TSHR (0.43) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8393413 0.94 TSHR (0.47) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8934225 0.94 TSHR (0.47) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8393416 0.94 TSHR (0.47) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8392970 0.86 CYP1A2 (0.50) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8392046 0.86 CYP1A2 (0.50) TSHRCYP3A4KDM4ELMNAABCB11
SCHEMBL8397236 0.86 CYP1A2 (0.53) TSHRCYP3A4KDM4ELMNAABCB11
Carbamic Acid SCHEMBL8397235 0.84 CYP1A2 (0.47) TSHRCYP3A4KDM4ELMNAABCB11
Carbamic Acid SCHEMBL8392184 0.80 CYP1A2 (0.60) CYP3A4SMN1; SMN2KMT2AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730576-A1 NOVEL CARBAMATE COMPOUNDS AND PROCESSES FOR PREPARING THE SAME YUKONG LIMITED (KR) 1996-09-11 EP disclosed
WO-1996009284-A1 NOVEL CARBAMATE COMPOUNDS AND PROCESSES FOR PREPARING THE SAME YUKONG LIMITED (KR) 1996-03-28 WO disclosed