Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960441 | 0.97 | S1PR1 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934081 | 0.97 | OPRL1 (0.34) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934318 | 0.96 | PTPN11 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934269 | 0.96 | PTPN11 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8933952 | 0.96 | PTPN11 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934090 | 0.96 | PTPN11 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934128 | 0.95 | S1PR1 (0.35) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934276 | 0.95 | OPRL1 (0.35) | OPRL1FFAR4DGAT1GRIN1GRIN2B | |
| SCHEMBL8960447 | 0.94 | FFAR4 (0.33) | S1PR1RARBRARASCN9AOPRL1 | |
| SCHEMBL8934171 | 0.94 | S1PR1 (0.35) | S1PR1RARBRARASCN9AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |