Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.72 |
| ▸ | VDR | P11473 | 8/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | GC | P02774 | 1/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352251 | 0.91 | MAPT (0.75) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL6403771 | 0.91 | MAPT (0.75) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL9455462 | 0.90 | MAPT (0.68) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL4901818 | 0.89 | MAPT (0.66) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL6407438 | 0.89 | MAPT (0.73) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL10616160 | 0.87 | MAPT (0.73) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL28789278 | 0.87 | MAPT (0.70) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL21128778 | 0.87 | MAPT (0.80) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL21264751 | 0.87 | MAPT (0.80) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL11977559 | 0.87 | MAPT (0.80) | MAPTSMN1; SMN2SREBF1VDRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030338-A1 | 1-SUBSTITUTED VITAMIN D3 ANALOGUES | THE JOHNS-HOPKINS UNIVERSITY (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996003994-A1 | 20(S)-22-OXA VITAMIN D3 ANALOGUES | THE JOHNS-HOPKINS UNIVERSITY (US) | 1996-02-15 | — | — | WO | disclosed |