Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.48 |
| ▸ | FNTB | P49356 | 7/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.48 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994759 | 0.91 | FNTA (0.56) | FNTAFNTBPGGT1BHTTATM | |
| SCHEMBL7996862 | 0.91 | FNTA (0.56) | FNTAFNTBPGGT1BHTTATM | |
| Hydrochloric Acid SCHEMBL8000351 | 0.90 | FNTA (0.55) | FNTAFNTBPGGT1BHTTATM | |
| Hydrochloric Acid SCHEMBL7994749 | 0.90 | FNTA (0.55) | FNTAFNTBPGGT1BHTTATM | |
| SCHEMBL8934701 | 0.88 | FNTA (0.44) | FNTAFNTBPGGT1BDDR2HTT | |
| SCHEMBL8934699 | 0.88 | FNTA (0.44) | FNTAFNTBPGGT1BDDR2HTT | |
| SCHEMBL7993175 | 0.87 | FNTA (0.48) | FNTAFNTBPGGT1BHTTMAPT | |
| SCHEMBL7993171 | 0.87 | FNTA (0.48) | FNTAFNTBPGGT1BHTTMAPT | |
| SCHEMBL7995119 | 0.87 | FNTA (0.48) | FNTAFNTBPGGT1BHTTMAPT | |
| Hydrochloric Acid SCHEMBL7982918 | 0.86 | FNTA (0.47) | FNTAFNTBPGGT1BHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |