Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934703 | 1.00 | KMT2A (0.40) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7993269 | 0.90 | MAPT (0.48) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7993272 | 0.90 | MAPT (0.48) | KMT2ANPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8869970 | 0.89 | MAPT (0.47) | KMT2ANPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8869964 | 0.89 | MAPT (0.47) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7994655 | 0.89 | FNTA (0.48) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7994657 | 0.89 | FNTA (0.48) | KMT2ANPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7993215 | 0.88 | FNTA (0.47) | KMT2ANPC1RAB9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7993213 | 0.88 | FNTA (0.47) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7993171 | 0.86 | FNTA (0.48) | KMT2ANPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |