Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896751 | 0.87 | BIRC5 (0.47) | ALDH1A1HTTBIRC5PRKD3PRKCG | |
| SCHEMBL5604900 | 0.87 | BIRC5 (0.47) | ALDH1A1HTTBIRC5PRKD3PRKCG | |
| SCHEMBL4885761 | 0.79 | CA1 (0.39) | ALDH1A1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL484192 | 0.78 | MYC (0.46) | ALDH1A1TSHRNOTUMHSP90AA1 | |
| SCHEMBL29826705 | 0.76 | BIRC5 (0.47) | ALDH1A1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL2187570 | 0.76 | BIRC5 (0.47) | ALDH1A1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL13483670 | 0.75 | BIRC5 (0.50) | ALDH1A1HTTBIRC5PRKD3PRKCG | |
| Methane SCHEMBL27922537 | 0.74 | BIRC5 (0.46) | ALDH1A1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL22649105 | 0.74 | TP53 (0.46) | ALDH1A1HTTBIRC5PRKD3PRKCG | |
| SCHEMBL27470054 | 0.73 | MCL1 (0.42) | BIRC5PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |